The properties of Peganum Harmala have antioxidant, anti-depressant and anti-inflammatory effects due to the alkaloids contained in it, including harmine and harmaline. In addition, harmala also contains compounds of flavonoids, phenols and amino acids that give it antibacterial and antifungal properties. In this article, we examine its history, properties, and use.
What is Peganum Harmala?
Peganum harmala or harmala is a medicinal plant that is several years old and grows mostly in arid and semi-arid regions such as Central Asia, the Middle East and North Africa. This plant has a branched stem and narrow and long leaves. The properties of Peganum Harmala are used in traditional medicine and religious practices.
Properties of Peganum Harmala:
- Anti-pain and inflammation: one of the most important properties of Peganum Harmala is its anti-inflammatory properties, which can be effective in treating inflammatory diseases such as arthritis. This plant is also used as a natural pain reliever in the treatment of various pains, including joint and muscle pain.
- Anti-depressant: The anti-depressant effects of harmala plant are due to the presence of chemical compounds such as harmaline and harmine. These compounds increase the level of dopamine and serotonin in the brain by inhibiting the monoamine oxidase enzyme, which helps improve mood and reduce depression symptoms.
- Anti-cancer: Research studies have shown that harmala can reduce the growth of cancer cells. These properties of harmala plant can be due to the presence of antioxidant and anti-inflammatory compounds in it, which also reduce the risk of cancer.
- Antifungal and microbial properties: Research has shown that Peganum harmala is very effective in treating many infections, especially skin infections, due to its antifungal and antimicrobial properties.
Application of Peganum Harmala:
The properties of Peganum Harmala (Harmala) are of great importance worldwide due to their potential therapeutic benefits. In addition, it is used as a sacred plant in religious ceremonies in many indigenous cultures.
- Traditional medicine: Harmala is often used in the traditional treatment of diseases such as anxiety, depression and digestive disorders.
- Psychoactive effects: Harmala plant has psychoactive effects due to its alkaloids. It is believed that it is used in spiritual ceremonies for its hallucinogenic properties. Also, the combination of this plant with other psychedelic plants of ayahuasca is used to increase its effects.
- Religious ceremonies: In Iran and some other countries, harmala smoke is used as a traditional ritual in religious celebrations and ceremonies to remove negative energies and sore eyes.
Disadvantages of Peganum Harmala:
The use of the properties of Peganum harmala in traditional treatments and religious ceremonies in different cultures has a long history, but its excessive use may be harmful. These disadvantages include:
- Drug interactions: Harmala may interact with antidepressants, antipsychotics, and some painkillers. Their simultaneous use can lead to interactions that have dangerous side effects.
- Allergic reaction: Some people may be allergic to the compounds in harmala plant. These allergic reactions can range from mild skin irritation to severe anaphylaxis.
- Side effects: Peganum harmala can cause side effects such as headache, dizziness, nausea and vomiting. It is possible that in some cases it may cause more serious side effects such as seizures and hallucinations.
- Overuse: Overuse of this plant may lead to risks such as heart palpitations, difficulty in breathing and even confusion.
- Legal consequences: Harmala consumption is illegal in some countries. Carrying or using it in these countries can have legal consequences.
- Dependence and Addiction: Long-term use of this plant can cause addiction and dependence, especially if it is used in high doses or with other substances, it will have serious consequences for the physical and mental health of a person.
In conclusion, research on the properties of Peganum harmala expands our understanding of its potential therapeutic benefits. With increasing interest in herbal remedies, harmala can become an important tool for treating many diseases. Also, harmala smoke and its psychedelic properties are valuable in religious ceremonies and holding healing rituals. The noteworthy point is the side effects and possible interactions of this herb with some medications, which are recommended to be used with caution and under the guidance of a qualified health care provider.
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